Disease: Blast Phase
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
TNFSF10 P50591 TNF superfamily member 10 Signaling 0.13 0.413 0.885
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TET2 Q6N021 tet methylcytosine dioxygenase 2 4.3E-54 0.458 0.808
STAT5B P51692 signal transducer and activator of transcription 5B Nucleic acid binding 1.00 0.442 0.808
STAT5A P42229 signal transducer and activator of transcription 5A Nucleic acid binding 1.00 0.445 0.808
SOCS3 O14543 suppressor of cytokine signaling 3 Enzyme modulator 0.75 0.434 0.808
SLCO6A1 Q86UG4 solute carrier organic anion transporter family member 6A1 Transporter 2.9E-11 0.412 0.885
SLC25A3 Q00325 solute carrier family 25 member 3 Transporter 7.5E-02 0.566 0.692
SH2B3 Q9UQQ2 SH2B adaptor protein 3 1.0E-04 0.527 0.692
SGSM3 Q96HU1 small G protein signaling modulator 3 Enzyme 3.4E-15 0.469 0.808
SF3B1 O75533 splicing factor 3b subunit 1 Nucleic acid binding 1.00 0.511 0.731
RUNX1T1 Q06455 RUNX1 partner transcriptional co-repressor 1 Transcription factor 0.98 0.530 0.808
RUNX1 Q01196 RUNX family transcription factor 1 Transcription factor 0.65 0.425 0.808
RBM45 Q8IUH3 RNA binding motif protein 45 2.1E-10 0.383 0.846
PTPA Q15257 protein phosphatase 2 phosphatase activator Enzyme modulator 0.99 0.480 0.846
PDGFRB P09619 platelet derived growth factor receptor beta Kinase 0.90 0.416 0.846
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923
MYB P10242 MYB proto-oncogene, transcription factor 0.82 0.490 0.692
MPL P40238 MPL proto-oncogene, thrombopoietin receptor Receptor 4.1E-09 0.510 0.692
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
MIR451A microRNA 451a 0.505 0.769